Neuroscience

Cardiovascular therapeutic area image

Central Nervous System (CNS) drug development is potentially one of the greatest challenges faced by researchers today, and Cisbio is committed to boosting your investigation efforts.

Working in close collaboration with leading scientists, we have developed a highly-specific range of assays to help you get the most out of your experiments.

 

Relevant Parkinson’s disease, Alzheimer’s disease, Huntington’s, Friedrich’s ataxia

Validated From cell culture to brain extract

Unique alpha synuclein, LRRK2

 

 

Neurogenerative diseases

Leading the way in neurodegenerative marker detection

Select your assay in this AD/PD pathway

 

Neuroinflammation

Neuroinflammation plays a role in many neurodegenerative disorders, such as multiple sclerosis (MS), Alzheimer's disease (AD), Parkinson's disease (PD), Huntington's disease (HD), amyotrophic lateral sclerosis (ALS), tauopathies, and age-related macular degeneration (ARMD).

Cisbio Bioassays offers a wide range of top quality tools, such as cytokine assays, allowing to save both time and precious samples in your neuroinflammation investigation.
 
 
 

 

Cell signaling

Cisbio offers a novel line of cell-based HTRF® pathway assays for investigating signaling activity by detecting phosphorylated and total proteins in a cellular environment. These assays provide an ideal functional pathway signaling solution for CNS, providing you with a rapid, streamlined alternative to more conventional technologies, such as Western Blot, ELISA, or other luminescent bead-based assays.

This complete offering of ready-to-use kits addresses the major pathways, including MAPK, JAK/STAT, and AKT.

 

 

Receptor binding

Cisbio Bioassays offers an effective and competitive alternative to radioligand binding assays for CNS research. Giving you optimal efficiency, our frozen cells are ready-to-use, pre-transfected, and pre-labeled.
These cells and ligands are available in catalog, they are validated for saturation binding assays and the Ki values are obtained with reference binders.

Our Tag-lite® technology is a non-radioactive, cellular platform that enables the investigation of natural ligand, small molecule or antibody binding to cell surface receptors. Tag-lite is highly advantageous for GPCR and RTK investigations, as well as biotherapeutic antibody development.