CXCR4R stably expressing cells
Tag-lite CXCR4 stably expressing cells
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CXCR4 is a receptor for the C-X-C chemokine CXCL12/SDF-1. Compelling evidences suggest that CXCR4 is nvolved in hematopoiesis and in cardiac ventricular septum formation. The receptor also plays an essential role in vascularization of the gastrointestinal tract.
CXCR4 acts as a coreceptor for human immunodeficiency virus-1/HIV-1. Cells expressing the CXCR4 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Watch this video explaining how to run a saturation binding assay using Tag-lite.
Watch this video explaining how to run a competitive binding assay using Tag-lite.
Examples of data obtained using Chemokine CXCR4 labeled cells and their matching fluorescent ligand (L0012RED). AMD-3100 was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
Evaluation of a Tag-lite binding assay for a class B receptor
In collaboration with Boehringer Ingelheim - Scientific Presentations
Ultra HTS at Bayer: use of IP-One and Tag-lite assays in GPCR drug discovery
In collaboration with Bayer - Scientific Presentations
The easy way to approach biology without radioactivity - Flyers
In collaboration with BioTek - Posters
Challenge the limits of binding kinetics studies - Application Notes
Understanding GPCRs is the key to improved DD
In collaboration with GEN - Guides
Tag-lite, the easiest solution for studying GPCR-ligands interactions
The gold standard technology for receptor binding studies - Videos
Kinetics of the ß2 Adrenergic receptor binding and signaling
A look at the kinetics of cAMP production in cells - Application Notes
All your HTRF assays in one document! - Catalog
A guide to Homogeneous Time Resolved Fluorescence
General principles of HTRF - Guides
How HTRF compares to Western Blot and ELISA
Get the brochure about technology comparison. - Brochures
Webinar | Association Rate Constant: The Unsung Hero of Drug Discovery Kinetics
Available On-demand - Videos
Product Insert CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Product Insert
Easy method for kinetic binding determination
How to revolutionize your kinetic binding demonstration with HTRF kinase binding platform assays - Application Notes
A comprehensive overview of pharmacology's main ligands - Guides
GPCRs: the pathway to Discovery
Complete solutions for GPCR Drug Discovery - Brochures
Safety Data Sheet CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Safety Data Sheet
Safety Data Sheet (DEU) CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Safety Data Sheet
Safety Data Sheet (ELL) CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Safety Data Sheet
Safety Data Sheet (FRA-FR) CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Safety Data Sheet
Safety Data Sheet (ITA) CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Safety Data Sheet
Safety Data Sheet (SPA) CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Safety Data Sheet
Safety Data Sheet (ENG-GB) CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Safety Data Sheet
Safety Data Sheet (ENG-US) CXCR4 LabCell / C1TT1CXCR4
C1TT1CXCR4 - Safety Data Sheet
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