An HTRF-based HTS system for discovery of inhibito...
Using HTRF based PPI assays as an alternative to traditional kinase assa...
Protein-protein interactions
The human interactome has been estimated to cover approximately 400,000 protein-protein interactions (PPI). These interactions are hot targets for the discovery of innovative drugs. Explore our articles, news, literature reviews, tips, and more on protein-protein interactions research.
Analysis of ubiquitin E3 ligase activity using sel...
Development of an HTRF assay for chararacterizing and quantifying E3 lig...
An HTRF assay for identifying inhibitors of hepati...
Setup of an HTRF assay using anti-tag reagents developed to discover sma...
Stoichiometry of a ligand-gated ion channel determ...
Binding between subunits within an oligomeric cell surface receptor can ...
Structural determination of estrogen-related recep...
Characterization of ligands found to be competitive for 4-hydroxytamoxif...
Use of homogeneous time-resolved fluorescence ener...
Validation of PPARg/Coactivator recruitment assay using reference inhibi...
Inhibition of early steps of HIV-1 replication by ...
By interacting with IN (viral integrase), NF5/Ini1 interferes with early...
Identification of ligands with bicyclic scaffolds ...
Development of an HTRF assay to screen library of ER agonists using PPI ...
Discovery of the first non-ATP competitive IGF-1R ...
Identification of inhibitors using an HTRF IGF-1R autophosphosphorylatio...