- Low sample consumption
- Faster and more convenient than ELISA
Glutamic acid decarboxylase (GAD) is an enzyme that catalyzes the decarboxylation of glutamate to GABA and CO2. GAD uses PLP as a cofactor. GAD67 is expressed in the brain, where GABA is used as a neurotransmitter, and in the insulin-producing ß-cells of the pancreas. GAD67 is a target of autoantibodies that can lead to the development of type 1 diabetes mellitus or latent autoimmune diabetes. Deregulation of GAD67 expression can be associated to Schizophrenia and Parkinson's disease. The GAD67 kit enables the fast detection of human, rat, or mouse GAD67 in cell lysates.