SNAP tag BB1 BombesinR cloned plasmid
Tag-lite plasmid cloned with a SNAP tag BB1 Bombesin receptor
Mammalian bombesin receptors comprise 3 subtypes: BB1, BB2, BB3. Activation of BB1 and BB2 receptors causes smooth-muscle contraction, appetite and feeding behavior changes.
Cells expressing the BB1 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Examples of data obtained using Bombesin BB1 labeled cells and their matching fluorescent ligand (L0038RED). [D-Tyr6,beta-Ala11,Phe13,Nle14] Bombesin 6-14 was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
In collaboration with Boehringer Ingelheim - Scientific Presentations
In collaboration with Bayer - Scientific Presentations
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Tag-lite plasmid cloned with a SNAP tag BB2 Bombesin (GRP) receptor