Tag-lite plasmid cloned with a SNAP tag BB1 Bombesin receptor
Bombesin BB2R expressing cells labeled with Terbium
- Fully functional cell line
- Transient expression
- Ready for binding
Mammalian bombesin receptors comprise 3 subtypes: BB1, BB2, BB3. Activation of BB1 and BB2 receptors causes smooth-muscle contraction, appetite and feeding behavior changes.
Cells expressing the BB2 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Examples of data obtained using Bombesin BB2 labeled cells and their matching fluorescent ligand (L0019RED). Bombesin was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
In collaboration with Boehringer Ingelheim - Scientific Presentations
In collaboration with Bayer - Scientific Presentations
Determination of association (kon) and dissociation (koff) rates constants using the Tag-lite platform
Challenge the limits of binding kinetics studies - Application Notes
Featuring a panel of experts - Videos
The gold standard technology for receptor binding studies - Videos
Tag-lite plasmid cloned with a SNAP tag BB2 Bombesin (GRP) receptor
Tag-lite cells expressing the Bombesin BB1 receptor with Terbium