Tag-lite cells expressing the Bradykinin B2 receptor with Terbium
Bradykinin B1R expressing cells labeled with Terbium
- Fully functional cell line
- Transient expression
- Ready for binding
Bradykinin receptor has two known isoforms bradykinin type 1 and 2 receptors. Both receptors are GPCR but mediate different actions. While B1R signaling promotes local tissue inflammation by recruiting neutrophils, B2R signaling is believed to downregulate the proliferation and growth of cells in VSMC and cardiomyocytes.
Cells expressing the B1 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
In collaboration with Boehringer Ingelheim - Scientific Presentations
In collaboration with Bayer - Scientific Presentations
Determination of association (kon) and dissociation (koff) rates constants using the Tag-lite platform
Challenge the limits of binding kinetics studies - Application Notes
Featuring a panel of experts - Videos
The gold standard technology for receptor binding studies - Videos