CCR5R expressing cells labeled with Terbium
- Fully functional cell line
- Transient expression
- Ready for binding
CCR5 or CC chemokine receptor 5 is a GPCR which regulates trafficking and effector functions of T-lymphocytes, macrophages, and dendritic cells. CCR acts as the coreceptor for the entry of HIV-1 and HIV-2.
Cells expressing the CCR5 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Examples of data obtained using CCR5 labeled cells and their matching fluorescent ligand (L0024RED). Mip1alpha was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
In collaboration with Boehringer Ingelheim - Scientific Presentations
In collaboration with Bayer - Scientific Presentations
Determination of association (kon) and dissociation (koff) rates constants using the Tag-lite platform
Challenge the limits of binding kinetics studies - Application Notes
Featuring a panel of experts - Videos
The gold standard technology for receptor binding studies - Videos
A look at the kinetics of cAMP production in cells - Application Notes