CCR5R expressing cells labeled with Terbium
- Fully functional cell line
- Transient expression
- Ready for binding
CCR5 or CC chemokine receptor 5 is a GPCR which regulates trafficking and effector functions of T-lymphocytes, macrophages, and dendritic cells. CCR acts as the coreceptor for the entry of HIV-1 and HIV-2.
Cells expressing the CCR5 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
- PRE-LABELED WITH TERBIUM
- FROZEN CELLS, READY TO BE USED
- CELLS/LIGAND VALIDATED FOR BINDING
Examples of data obtained using CCR5 labeled cells and their matching fluorescent ligand (L0024RED). Mip1alpha was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
In collaboration with Boehringer Ingelheim - Scientific Presentations
In collaboration with Bayer - Scientific Presentations
Determination of association (kon) and dissociation (koff) rates constants using the Tag-lite platform
Challenge the limits of binding kinetics studies - Application Notes
Featuring a panel of experts - Videos
The gold standard technology for receptor binding studies - Videos
A look at the kinetics of cAMP production in cells - Application Notes
Get the brochure about technology comparison. - Brochures
Available On-demand - Videos