Dopamine D2R stably expressing cells
Tag-lite Dopamine D2 stably expressing cells
Deregulation of the Dopamine D3 receptor, a GPCR, plays a key role in different neurological disorders. There is compelling evidences that the Dopamine D3 receptor is involved in a number of pathological conditions, including schizophrenia, Parkinson's disease, addiction, anxiety, depression and glaucoma.
Cells expressing the D3A receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Examples of data obtained using Dopamine D3a labeled cells and their matching fluorescent ligand (L0002RED). (+/-)PPHT was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
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Tag-lite plasmid cloned with a SNAP tag D1 Dopamine type 1 receptor
Tag-lite plasmid cloned with a SNAP tag D2 Dopamine type 2 receptor
Tag-lite cells expressing the Dopamine D1 receptor with Terbium