Serotonin 5HT1AR fluorescent probe
Tag-lite Serotonin 5HT1A receptor fluorescent probe
5-HT2C receptors are located on postsynaptic neurons. Compelling evdience suggest that the 5-HT2C GPCR plays a role in the control of many physiological processes , including feeding, anxiety, temperature regulation, locomotion, sexual behavior and the occurrence of seizures.
Cells expressing the 5HT2C receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Examples of data obtained using Serotonin 5HT2C labeled cells and their matching fluorescent ligand (L0066GRE). Mianserin hydrochloride was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
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Plasmid cloned with a SNAP tag 5HT1A 5-Hydroxytryptamine 1A receptor
Plasmid cloned with a SNAP tag 5HT1B 5-Hydroxytryptamine 1B receptor
Plasmid cloned with a SNAP tag 5HT2C 5-Hydroxytryptamine 2C receptor
Tag-lite cell Serotonin 5HT1A receptor labeled with Terbium
Tag-lite cells expressing the Serotonin 5HT1B receptor with Terbium