Serotonin 5HT1AR fluorescent probe
Tag-lite Serotonin 5HT1A receptor fluorescent probe
The 5-HT1B receptor is a GPCR widely distributed in regions that receive serotonergic input, including the frontal cortex, septum, amygdala, hippocampus, and hypothalamus. The serotonin 1B receptor (5-HT1B) plays a role HTR1B gene plays a relevant role in substance-related and obsessive compulsive disorders.
Cells expressing the 5HT1B receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementionned receptor.
Examples of data obtained using Serotonin 5HT1B labeled cells and their matching fluorescent ligand (L0045RED) . GR-127935 was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
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Plasmid cloned with a SNAP tag 5HT1A 5-Hydroxytryptamine 1A receptor
Plasmid cloned with a SNAP tag 5HT1B 5-Hydroxytryptamine 1B receptor
Plasmid cloned with a SNAP tag 5HT2C 5-Hydroxytryptamine 2C receptor
Tag-lite cell Serotonin 5HT1A receptor labeled with Terbium
Tag-lite cells expressing the Serotonin 5HT2C receptor with Terbium