Dopamine D2 and D3aR fluorescent probe
Tag-lite Dopamine D2 & D3a receptors fluorescent probe
-->
Dopaminergic neurons and dopamine receptors are the most numerous in brain. In the brain, dopamine receptors D1 and D2 are GPCR responsible for such crucial processes as voluntary movement, sleep, regulation of food intake, attention, learning, and working memory.
Cells expressing the D2 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Watch this video explaining how to run a saturation binding assay using Tag-lite.
Watch this video explaining how to run a competitive binding assay using Tag-lite.
Examples of data obtained using Dopamine D2 labeled cells and their matching fluorescent ligand (L0002RED). Bromocriptine was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
Evaluation of a Tag-lite binding assay for a class B receptor
In collaboration with Boehringer Ingelheim - Scientific Presentations
Ultra HTS at Bayer: use of IP-One and Tag-lite assays in GPCR drug discovery
In collaboration with Bayer - Scientific Presentations
The easy way to approach biology without radioactivity - Flyers
Challenge the limits of binding kinetics studies - Application Notes
Understanding GPCRs is the key to improved DD
In collaboration with GEN - Guides
Tag-lite, the easiest solution for studying GPCR-ligands interactions
The gold standard technology for receptor binding studies - Videos
Kinetics of the ß2 Adrenergic receptor binding and signaling
A look at the kinetics of cAMP production in cells - Application Notes
All your HTRF assays in one document! - Catalog
A guide to Homogeneous Time Resolved Fluorescence
General principles of HTRF - Guides
How HTRF compares to Western Blot and ELISA
Get the brochure about technology comparison. - Brochures
Webinar | Association Rate Constant: The Unsung Hero of Drug Discovery Kinetics
Available On-demand - Videos
Product Insert DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Product Insert
Molecular basis of neuroinflammation and neurodegeneration diseases
The essential guide for extending your knowledge on the molecular mechanisms of neurodegenerative diseases - Guides
Easy method for kinetic binding determination
How to revolutionize your kinetic binding demonstration with HTRF kinase binding platform assays - Application Notes
A comprehensive overview of pharmacology's main ligands - Guides
GPCRs: the pathway to Discovery
Complete solutions for GPCR Drug Discovery - Brochures
Safety Data Sheet DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Safety Data Sheet
Safety Data Sheet (DEU) DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Safety Data Sheet
Safety Data Sheet (ELL) DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Safety Data Sheet
Safety Data Sheet (FRA-FR) DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Safety Data Sheet
Safety Data Sheet (ITA) DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Safety Data Sheet
Safety Data Sheet (SPA) DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Safety Data Sheet
Safety Data Sheet (ENG-GB) DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Safety Data Sheet
Safety Data Sheet (ENG-US) DopaD2-R LabCell / C1TT1D2
C1TT1D2 - Safety Data Sheet
Choosing the right microplate reader ensures you’ll get an optimal readout. Discover our high performance reader, or verify if your lab equipment is going to be compatible with this detection technology.
Let's find your readerYou might be interested in