Phospho- and total LRRK2 assays to study Parkinson’s disease
LRRK2 is a significant target in neuroscience research involving Parkinson’s disease (PD) and neurodegenerative disorders in general.
LRRK2 mutations have been linked to the genetic development of Parkison’s. LRRK2 has also been involved in the phosphorylation of Tau protein, leading to its aggregation and onset of dementia.
Cisbio provides an accurate solution to investigate the cellular LRRK2 state of phosphorylation with our cell-based phospho LRRK2 (Ser935) assay combined with Total LRRK2 assay used to normalize against steady-state expression.
These assays are part of our CNS range including Tau phosphorylation and Tau aggregation assays.