GIPR fluorescent probe
Tag-lite GIP receptor fluorescent probe
Gastric inhibitory polypeptide receptor or GIP is a GPCR expressed in the pancreas, stomach, small intestine, adipose tissue. The GIP receptor is a member of the secretin–VIP family of GPCR. GIP, known as glucose-dependent insulinotropic polypeptide, is released by K cells in the small intestine in response to food.
Cells expressing the GIPR receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Examples of data obtained using Glucagon GIPR labeled cells and their matching fluorescent ligand (L0018RED). GIP was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
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The gold standard technology for receptor binding studies - Videos
A look at the kinetics of cAMP production in cells - Application Notes
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How to revolutionize your kinetic binding demonstration with HTRF kinase binding platform assays - Application Notes