GIPR fluorescent probe
Tag-lite GIP receptor fluorescent probe
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Gastric inhibitory polypeptide receptor or GIP is a GPCR expressed in the pancreas, stomach, small intestine, adipose tissue. The GIP receptor is a member of the secretin–VIP family of GPCR. GIP, known as glucose-dependent insulinotropic polypeptide, is released by K cells in the small intestine in response to food.
Cells expressing the GIPR receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Watch this video explaining how to run a saturation binding assay using Tag-lite.
Watch this video explaining how to run a competitive binding assay using Tag-lite.
Examples of data obtained using Glucagon GIPR labeled cells and their matching fluorescent ligand (L0018RED). GIP was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
Evaluation of a Tag-lite binding assay for a class B receptor
In collaboration with Boehringer Ingelheim - Scientific Presentations
Ultra HTS at Bayer: use of IP-One and Tag-lite assays in GPCR drug discovery
In collaboration with Bayer - Scientific Presentations
The easy way to approach biology without radioactivity - Flyers
Challenge the limits of binding kinetics studies - Application Notes
Understanding GPCRs is the key to improved DD
In collaboration with GEN - Guides
Tag-lite, the easiest solution for studying GPCR-ligands interactions
The gold standard technology for receptor binding studies - Videos
Kinetics of the ß2 Adrenergic receptor binding and signaling
A look at the kinetics of cAMP production in cells - Application Notes
All your HTRF assays in one document! - Catalog
A guide to Homogeneous Time Resolved Fluorescence
General principles of HTRF - Guides
How HTRF compares to Western Blot and ELISA
Get the brochure about technology comparison. - Brochures
Webinar | Association Rate Constant: The Unsung Hero of Drug Discovery Kinetics
Available On-demand - Videos
Product Insert GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Product Insert
Easy method for kinetic binding determination
How to revolutionize your kinetic binding demonstration with HTRF kinase binding platform assays - Application Notes
A comprehensive overview of pharmacology's main ligands - Guides
GPCRs: the pathway to Discovery
Complete solutions for GPCR Drug Discovery - Brochures
Safety Data Sheet GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Safety Data Sheet
Safety Data Sheet (DEU) GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Safety Data Sheet
Safety Data Sheet (ELL) GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Safety Data Sheet
Safety Data Sheet (FRA-FR) GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Safety Data Sheet
Safety Data Sheet (ITA) GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Safety Data Sheet
Safety Data Sheet (SPA) GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Safety Data Sheet
Safety Data Sheet (ENG-GB) GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Safety Data Sheet
Safety Data Sheet (ENG-US) GIPR-R LabCell / C1TT1GIPR
C1TT1GIPR - Safety Data Sheet
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