Tag-lite Histamine H1 receptor fluorescent probe
Histamine H1R expressing cells labeled with Terbium
- Fully functional cell line
- Transient expression
- Ready for binding
The histamine H1 receptors are distributed in several tissues, including the brain and the smooth muscles from airways. Stimulation of histamine H1 leads to the synthesis and release of several neurochemicals and neuromodulators.
Cells expressing the H1 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Examples of data obtained using Histamine H1 labeled cells and their matching fluorescent ligand (L0015GRE). Doxepin was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
In collaboration with Boehringer Ingelheim - Scientific Presentations
In collaboration with Bayer - Scientific Presentations
Determination of association (kon) and dissociation (koff) rates constants using the Tag-lite platform
Challenge the limits of binding kinetics studies - Application Notes
Featuring a panel of experts - Videos
The gold standard technology for receptor binding studies - Videos
A look at the kinetics of cAMP production in cells - Application Notes