Tag-lite Histamine H1 stably expressing cells
Histamine H3R expressing cells labeled with Terbium
- Fully functional cell line
- Transient expression
- Ready for binding
Histamine H3 receptors are GPCR located on the presynaptic membranes and cell soma of histamine neurons. In the brain, stimulation of histamine H3 receptors negatively regulate the synthesis and release of histamine.
Cells expressing the H3 receptor are provided pre-labeled with Terbium, and can be used to conduct receptor binding studies on the aforementioned receptor.
Examples of data obtained using Histamine H3 labeled cells and their matching fluorescent ligand (L0052RED). Clobenpropit was used as reference ligand. Results may vary from one HTRF® compatible reader to another.
In collaboration with Boehringer Ingelheim - Scientific Presentations
In collaboration with Bayer - Scientific Presentations
Determination of association (kon) and dissociation (koff) rates constants using the Tag-lite platform
Challenge the limits of binding kinetics studies - Application Notes
Featuring a panel of experts - Videos
The gold standard technology for receptor binding studies - Videos
A look at the kinetics of cAMP production in cells - Application Notes
Tag-lite Histamine H1 receptor fluorescent probe
Tag-lite Histamine H3 receptor fluorescent probe
Tag-lite plasmid cloned with a SNAP tag H1 Histamine receptor
Tag-lite plasmid cloned with a SNAP tag H3 Histamine receptor