Active renin radioimmunometric assay kit
Assess and monitor hypertensive patients
Find the causes of high blood pressure (hypertension)
Differentially diagnose between primary and secondary hyperaldosteronism
Assess patient response to antihypertensive treatment
Diagnosis unilateral stenosis of the renal artery
Detect ectopic production of renin in cases of cancer associated with hypertension
The Endocrine Society recommends using the aldosterone/renin ratio to detect primary aldosteronism.
*Funder JW et al. J Clin Endocrinol Metab. 2008;93(9): 3266-81.
- ONLY ONE INCUBATION FOR ALL PATHOLOGIES
- EASY CONVERSION FROM PRA METHODS
- HIGH PRECISION IN LOW CONCENTRATIONS
Two monoclonal antibodies are used for the sandwich. The first monoclonal antibody is coated onto the walls of the tube, while the second one is radiolabelled with iodine-125.
One-step assay procedure: 3h at RT / shaking.
Working range: 0 – 320 pg/mL (IRP 68/356 IU = CIS pg/mL x 1.8.10-6) Sample: EDTA Plasma - 300 µL
Analytical sensitivity: 1 pg/mL
Functional sensitivity: 5 pg/mL
|Upright||20 - 40||50||13.10||5.1 - 38.7|
|40 - 60||75||14.02||1.8 - 59.4|
|Supine||20 - 40||50||8.11||3.6 - 20.1|
|40 - 60||75||6.18||1.1 - 20.2|