TNFα, mainly produced by activated macrophages, is one of the main cytokines in acute phase reaction. Depending on the cellular target and the biological context, TNFα can activate pro-apoptosis or pro-survival pathways, thus regulating tissue development through apoptosis control.
Outside of Oncology and Inflammation, TNFα contributes to the development of Type II Diabetes by increasing insulin resistance and modulating fatty acid metabolism.
Cisbio's Cynomolgus TNFα kit is a homogeneous, add and read assay to measure TNFα secretion in supernatant. It offers a fast, efficient alternative to ELISA.
|Sample size||16 µL|
|Final assay volume||20 µL|
|Kit components||Lyophilized standard, frozen detection antibodies, buffers & protocol.|
|LOD & LOQ (in Diluent)||12.4 pg/mL & 27 pg/mL|
|Range||27 – 3,000 pg/mL|
|Time to result||ON at RT|