Cytokine secretion profile on PBMCs

Maité Romier, Fabienne Charrier-Savournin, Laurence Jacquemart, Christelle Catone

Cisbio, Codolet, France

PBMC (peripheral blood mononuclear cells) have become the model of choice in Oncology & Immuno-Oncology. They regroup T cells, B cells, NK cells and monocytes, and are used from academic research to drug discovery as physiological representations of the immune system’s response to treatment (cytokine storm, T cell activation …).
Multiple cytokines have to be monitored in parallel to understand how the immune system is affected and reacting to treatment.
This poster will show you how to take advantage of Cisbio’s cytokine kits’ small sample consumption and protocol homogeneity to build the cytokine panel best suited to your research.