IL1β, also known as leukocytic pyrogen or mononuclear cell factor, is a pro-inflammatory cytokine of the IL1 family.
IL1β is considered to be a major endogenous pyrogen and induces prostaglandin synthesis, T cell activation, B cell activation and subsequent antibody production. It is also a known promoter of T cell differentiation into Th17.
Cisbio's Human IL1β kit is a homogeneous, add and read assay to measure IL1β secretion in supernatant. It offers a fast, efficient alternative to ELISA.
|Sample size||16 µL|
|Final assay volume||20 µL|
|Kit components||Lyophilized standard, frozen detection antibodies, buffers & protocol.|
|LOD & LOQ (in Diluent)||5 pg/mL & 39.4 pg/mL|
|Range||39.4 – 6,500 pg/mL|
|Time to result||Overnight at RT|
|Calibration||NIBSC (86/680) value (IU/mL) = 0,1 x HTRF hIL1β value (pg/mL)|