Phospho- and total IRS1 assays for monitoring Insulin resistance
Cisbio's cell-based homogeneous HTRF® phospho- and total IRS1 assays enable quantitative detection of the modulation of IRS1 phosphorylated on Serine 307 in mouse cells and on Serine 312 in human cells.
IRS1, relevant marker for insulin resistance, tumor development and metastatic progression, is associated with type 2 diabetes, obesity and cancer. Using a streamlined protocol without any washing steps and amenable to low-volume formats, phospho- and total IRS1 assays can be used from basic research up to preclinical drug discovery phases. These kits contains all the reagents you need, and offer increased throughput compared to ELISA or Western Blot.