HTRF® cell-based immunoassay for quantification of total and phospho-STAT1 in JAK/STAT signaling
Cisbio's cell-based homogeneous HTRF® phospho-STAT1 assay (Tyr701) is designed for the quantitative detection of STAT1 modulation phosphorylated on tyrosine 701, while the HTRF® total STAT1 assay is designed for the quantitative detection of STAT1 modulation. Stimulated by growth factors and chemokines, like IFN-γ induced JAK/STAT signaling, STAT1 acts as an important transcriptional activator. Thus the assay serves as a readout for JAK inhibitors in oncology, infectiology, and inflammation.
The phospho-STAT1 and total STAT1 ready-to-use kits contain all the reagents you need and offer enhanced convenience over other immunoassay technologies, being easily amenable to high throughput screening and automated platforms.