cAMP Gs dynamic kit
Optimal performance when applied to Gs activation or inhibition
LTB4 is a major leukotriene product that is enzymatically derived from the arachidonic acid cascade. LTB4 is synthesized by leukocytes via the 5-lipoxygenase pathway and mediates different leukocyte functions such as lysosomal enzyme release, adhesion, and aggregation of polymorphonuclear leukocytes. LTB4 has been described as a potent mediator of inflammatory diseases and immunoregulation. The LTB4 kit enables the monitoring of LTB4 produced by cells and can be used to study the LTA4-hydrolase.
|Incubation||1h at RT|
|Assay range||0.15 166.67 ng/mL|
|Detection limit||0.15 ng/mL|
|Specificity||Low cross reactivity with 6-trans 12 epi LTB4|
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