A review of applications to the study of molecular interactions involved...
PAb Anti Human IgG-Eu cryptate HTRF®
- High affinity
IgGs from goat anti-Human immunoserum were immunopurified and labeled with Eu. PAb Anti Human IgG-Eu cryptate may be used to detect the binding of unlabeled human specific antibody on a target molecule or on Ig fusion proteins.
This reagent can be used in both biochemical and cellular formats to study a wide variety of interactions: protein/protein, protein/peptide, protein/DNA, protein/RNA, protein/carbohydrate, protein/small molecule, receptor/ligand.
HTRF can detect a broad range of affinity constants ranging from picomolar to low millimolar.
- LARGE COMPLEXES DETECTION
- BATCH-TO-BATCH REPRODUCIBILITY
- LOW TO HIGH KD DETECTION
In collaboration with Bristol Myers Squibb - Scientific Presentations
Benefit from unlimited flexibility for your assay development - Flyers
In collaboration with Boehringer Ingelheim - Posters
In collaboration with Sanofi - Posters
Every interaction is within range - Technical Notes
Easy pharmacological characterization of PPI modulators. - Technical Notes
Deciphering low- and high affinity interactions - Application Notes
Monitoring nuclear receptor binding with HTRF assays - Application Notes
Challenge large complexes with HTRF assays - Application Notes
Get the brochure about technology comparison. - Brochures
See how peer researchers challenge the viral life cycle with PPI assays - Application Notes
Plate Reader Requirement
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HTRF, a generic mthod in the study of protein-protein interactions
HTRF, a way to identify specific conformation protease inhibitors