Identification of cytokine-signaling inhibitors contributes a great deal...
Streptavidin-XL665 HTRF®
XL665-labeled Streptavidin for capturing biotinylated proteins, peptides, antibodies, small molecules, nucleic acids....
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No-wash
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Ease-of-use
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High affinity
Overview
Streptavidin has been labeled with XL665. Biotin binds to Streptavidin with high affinity (Ka=1015M-1). The binding is rapid and stable, making it an ideal choice for use in a variety of assays such as enzyme assays, protein-protein binding assays and molecular biology assays.
Benefits
- LARGE COMPLEXES DETECTION
- BATCH-TO-BATCH REPRODUCIBILITY
- LOW TO HIGH KD DETECTION
Assay principle
Assay protocol
The example on the right describes the protocol using a 20 µL final assay volume for detecting an interaction between a biotinylated-tagged partner A and a non-tagged partner B*.
Dispense the 2 partners (10 µL), incubate, add Streptavidin-XL (5 µL) and anti-partner B labeled with donor (5 µL), incubate and read.
*partner B can also be tagged, Fc fused or directly labeled. In these cases use for the detection, the corresponding HTRF reagent (anti-Tag, anti species, protA, Streptavidin), labeled with donor.
Build HTRF interaction assays for your specific application
How do the number of tests relate to active moiety?
Recommended quantities of Cryptate and XL665 conjugates
Exploiting HTRF for novel drug classes: Stabilizing 14-3-3 protein-protein interactions
In collaboration with Lead Discovery Center GmbH - Scientific Presentations
Experience the freedom of building your own assay
HTRF kinase activity toolbox reagents - Flyers
HTRF protein-protein interaction reagents
Benefit from unlimited flexibility for your assay development - Flyers
Addressing the interactome with protein-protein assays
Cover all PPIs with one approach - Brochures
HTRF -A Beneficial Tool for Lead Optimization of Biotherapeutics
In collaboration with Boehringer Ingelheim - Posters
Setting-up HTRF technology for G9a & DNMT1 High-Throughput Screening
In collaboration with Universidad de Navarra - Posters
The ultimate guide to PPI assays with HTRF
Complete guide - Guides
Guidelines for optimizing protein-protein interaction assays using HTRF PPI reagents
Every interaction is within range - Technical Notes
Product Insert Streptavidin-XL / 610SAXLF-610SAXLA-610SAXLB
610SAXLF-610SAXLA-610SAXLB - Product Insert
HTRF PPI your dream assay served on a plate
Sandwiches aren't just for eating - Infographics
Best practices for pharmacological characterization of PPI inhibitors
Easy pharmacological characterization of PPI modulators. - Technical Notes
HTRF assays handle low- to high affinity protein-protein interactions
Deciphering low- and high affinity interactions - Application Notes
Nuclear receptor ligand identification with HTRF
Monitoring nuclear receptor binding with HTRF assays - Application Notes
HTRF addresses large protein-protein interaction complexes
Challenge large complexes with HTRF assays - Application Notes
A brief history of Protein-Protein Interactions
How well do you know PPI? - Infographics
All your HTRF assays in one document! - Catalog
A guide to Homogeneous Time Resolved Fluorescence
General principles of HTRF - Guides
How HTRF compares to Western Blot and ELISA
Get the brochure about technology comparison. - Brochures
Virology research solutions using HTRF Protein-Protein Interaction assays
See how peer researchers challenge the viral life cycle with PPI assays - Application Notes
Advance your CAR-T cell research - Flyers
Batch Information Streptavidin-XL / 20280911
610SAXAC Batch 146A - Batch Information
Batch Information Streptavidin-XL / 20250615
610SAXAC Batch 140B - Batch Information
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Batch Information Streptavidin-XL / 20280608
610SAXAC Batch 145A - Batch Information
Safety Data Sheet Streptavidin-XL / 610SAXAC
610SAXAC - Safety Data Sheet
Batch Information Streptavidin-XL / 20290614
610SAXAC Batch 150A - Batch Information
Batch Information Streptavidin-XL / 20291125
610SAXAC Batch 154 - Batch Information
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610SAXAC Batch 158B - Batch Information
Batch Information Streptavidin-XL / 20300401
610SAXAC Batch 160A - Batch Information
Batch Information Streptavidin-XL / 20301123
610SAXAC Batch 165A - Batch Information
Safety Data Sheet (DEU) Streptavidin-XL / 610SAXAC
610SAXAC - Safety Data Sheet
Safety Data Sheet (ELL) Streptavidin-XL / 610SAXAC
610SAXAC - Safety Data Sheet
Safety Data Sheet (FRA-FR) Streptavidin-XL / 610SAXAC
610SAXAC - Safety Data Sheet
Safety Data Sheet (ITA) Streptavidin-XL / 610SAXAC
610SAXAC - Safety Data Sheet
Safety Data Sheet (SPA) Streptavidin-XL / 610SAXAC
610SAXAC - Safety Data Sheet
Safety Data Sheet (ENG-GB) Streptavidin-XL / 610SAXAC
610SAXAC - Safety Data Sheet
Safety Data Sheet (ENG-US) Streptavidin-XL / 610SAXAC
610SAXAC - Safety Data Sheet
Batch Information Streptavidin-XL / 20310816
610SAXAC Batch 170B - Batch Information
Batch Information Streptavidin-XL / 20310707
610SAXAC Batch 170A - Batch Information
Batch Information Streptavidin-XL / 20310420
610SAXAC Batch 167C - Batch Information
Batch Information Streptavidin-XL / 20310829
610SAXAC Batch 170C - Batch Information
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610SAXAC Batch 172A - Batch Information
Batch Information Streptavidin-XL / 20300909
610SAXAC Batch 163 - Batch Information
Batch Information Streptavidin-XL / 20320129
610SAXAC Batch 173A - Batch Information
Safety Data Sheet Streptavidin-XL / 610SAXLA
610SAXLA - Safety Data Sheet
Safety Data Sheet (DEU) Streptavidin-XL / 610SAXLA
610SAXLA - Safety Data Sheet
Safety Data Sheet (ELL) Streptavidin-XL / 610SAXLA
610SAXLA - Safety Data Sheet
Safety Data Sheet (FRA-FR) Streptavidin-XL / 610SAXLA
610SAXLA - Safety Data Sheet
Safety Data Sheet (ITA) Streptavidin-XL / 610SAXLA
610SAXLA - Safety Data Sheet
Safety Data Sheet (SPA) Streptavidin-XL / 610SAXLA
610SAXLA - Safety Data Sheet
Safety Data Sheet (ENG-GB) Streptavidin-XL / 610SAXLA
610SAXLA - Safety Data Sheet
Safety Data Sheet (ENG-US) Streptavidin-XL / 610SAXLA
610SAXLA - Safety Data Sheet
Batch Information Streptavidin-XL / 20220905
610SAXLA Batch 152A - Batch Information
Batch Information Streptavidin-XL / 20221127
610SAXLA Batch 154A - Batch Information
Batch Information Streptavidin-XL / 20230212
610SAXLA Batch 158A - Batch Information
Batch Information Streptavidin-XL / 20230212
610SAXLA Batch 158B - Batch Information
Batch Information Streptavidin-XL / 20230514
610SAXLA Batch 161A - Batch Information
Batch Information Streptavidin-XL / 20231002
610SAXLA Batch 164A - Batch Information
Batch Information Streptavidin-XL / 20240128
610SAXLA Batch 167A - Batch Information
Batch Information Streptavidin-XL / 20240708
610SAXLA Batch 170A - Batch Information
Safety Data Sheet Streptavidin-XL / 610SAXLB
610SAXLB - Safety Data Sheet
Safety Data Sheet (DEU) Streptavidin-XL / 610SAXLB
610SAXLB - Safety Data Sheet
Safety Data Sheet (ELL) Streptavidin-XL / 610SAXLB
610SAXLB - Safety Data Sheet
Safety Data Sheet (FRA-FR) Streptavidin-XL / 610SAXLB
610SAXLB - Safety Data Sheet
Safety Data Sheet (ITA) Streptavidin-XL / 610SAXLB
610SAXLB - Safety Data Sheet
Safety Data Sheet (SPA) Streptavidin-XL / 610SAXLB
610SAXLB - Safety Data Sheet
Safety Data Sheet (ENG-GB) Streptavidin-XL / 610SAXLB
610SAXLB - Safety Data Sheet
Safety Data Sheet (ENG-US) Streptavidin-XL / 610SAXLB
610SAXLB - Safety Data Sheet
Batch Information Streptavidin-XL / 20230116
610SAXLB Batch 157A - Batch Information
Batch Information Streptavidin-XL / 20230212
610SAXLB Batch 158A - Batch Information
Batch Information Streptavidin-XL / 20230514
610SAXLB Batch 161A - Batch Information
Batch Information Streptavidin-XL / 20231211
610SAXLB Batch 166A - Batch Information
Batch Information Streptavidin-XL / 20240708
610SAXLB Batch 170A - Batch Information
Batch Information Streptavidin-XL / 20250511
610SAXLB Batch 174A - Batch Information
Safety Data Sheet (DEU) Streptavidin-XL / 610SAXLF
610SAXLF - Safety Data Sheet
Safety Data Sheet (ELL) Streptavidin-XL / 610SAXLF
610SAXLF - Safety Data Sheet
Safety Data Sheet (FRA-FR) Streptavidin-XL / 610SAXLF
610SAXLF - Safety Data Sheet
Safety Data Sheet (ITA) Streptavidin-XL / 610SAXLF
610SAXLF - Safety Data Sheet
Safety Data Sheet (SPA) Streptavidin-XL / 610SAXLF
610SAXLF - Safety Data Sheet
Safety Data Sheet (ENG-GB) Streptavidin-XL / 610SAXLF
610SAXLF - Safety Data Sheet
Safety Data Sheet (ENG-US) Streptavidin-XL / 610SAXLF
610SAXLF - Safety Data Sheet
Batch Information Streptavidin-XL / 20230212
610SAXLF Batch 158A - Batch Information
Batch Information Streptavidin-XL / 20230514
610SAXLF Batch 161A - Batch Information
Batch Information Streptavidin-XL / 20240708
610SAXLF Batch 170A - Batch Information
Safety Data Sheet Streptavidin-XL / 610SAXLG
610SAXLG - Safety Data Sheet
Safety Data Sheet (DEU) Streptavidin-XL / 610SAXLG
610SAXLG - Safety Data Sheet
Safety Data Sheet (ELL) Streptavidin-XL / 610SAXLG
610SAXLG - Safety Data Sheet
Safety Data Sheet (FRA-FR) Streptavidin-XL / 610SAXLG
610SAXLG - Safety Data Sheet
Safety Data Sheet (ITA) Streptavidin-XL / 610SAXLG
610SAXLG - Safety Data Sheet
Safety Data Sheet (SPA) Streptavidin-XL / 610SAXLG
610SAXLG - Safety Data Sheet
Safety Data Sheet (ENG-GB) Streptavidin-XL / 610SAXLG
610SAXLG - Safety Data Sheet
Safety Data Sheet (ENG-US) Streptavidin-XL / 610SAXLG
610SAXLG - Safety Data Sheet
Batch Information Streptavidin-XL / 20220905
610SAXLG Batch 152A - Batch Information
Batch Information Streptavidin-XL / 20221106
610SAXLG Batch 153A - Batch Information
Batch Information Streptavidin-XL / 20221127
610SAXLG Batch 154A - Batch Information
Batch Information Streptavidin-XL / 20221211
610SAXLG Batch 155A - Batch Information
Batch Information Streptavidin-XL / 20230107
610SAXLG Batch 156A - Batch Information
Batch Information Streptavidin-XL / 20230116
610SAXLG Batch 157A - Batch Information
Batch Information Streptavidin-XL / 20230212
610SAXLG Batch 158A - Batch Information
Batch Information Streptavidin-XL / 20230212
610SAXLG Batch 158B - Batch Information
Batch Information Streptavidin-XL / 20230308
610SAXLG Batch 159A - Batch Information
Batch Information Streptavidin-XL / 20230403
610SAXLG Batch 160A - Batch Information
Batch Information Streptavidin-XL / 20230525
610SAXLG Batch 161A - Batch Information
Batch Information Streptavidin-XL / 20230525
610SAXLG Batch 161B - Batch Information
Batch Information Streptavidin-XL / 20230728
610SAXLG Batch 162B - Batch Information
Batch Information Streptavidin-XL / 20230728
610SAXLG Batch 162A - Batch Information
Batch Information Streptavidin-XL / 20230911
610SAXLG Batch 163A - Batch Information
Batch Information Streptavidin-XL / 20230911
610SAXLG Batch 163B - Batch Information
Batch Information Streptavidin-XL / 20231002
610SAXLG Batch 164A - Batch Information
Batch Information Streptavidin-XL / 20231211
610SAXLG Batch 166A - Batch Information
Batch Information Streptavidin-XL / 20240128
610SAXLG Batch 167A - Batch Information
Batch Information Streptavidin-XL / 20240304
610SAXLG Batch 168A - Batch Information
Batch Information Streptavidin-XL / 20240623
610SAXLG Batch 169A - Batch Information
Batch Information Streptavidin-XL / 20250130
610SAXLG Batch 173A - Batch Information
Batch Information Streptavidin-XL / 20250511
610SAXLG Batch 174A - Batch Information
Plate Reader Requirement
Choosing the right microplate reader ensures you’ll get an optimal readout. Discover our high performance reader, or verify if your lab equipment is going to be compatible with this detection technology.
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